Immunochemical investigations of human pituitary growth hormone.
نویسندگان
چکیده
Earlier immunological investigations of growth hormone (somatotropin) isolated from bovine and human pituitaries showed that these two protein hormone preparations form speciesspecific antibodies, as evidenced by the results of precipitin ring tests with rabbit antiserum and of anaphylactic shock experiments in guinea pigs (1, 2). It was further demonstrated that the rabbit antiserum exerts in hypophysectomized rats an antihormone activity specific for the particular growth hormone concerned. This paper presents quantitative data on the antigen-antibody complex of human growth hormone. In addition, the growth hormone content of human pituitary glands has been quantitatively determined on the basis of the immunochemical reaction of the hormone.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 235 شماره
صفحات -
تاریخ انتشار 1960